Scientific papers for your Perusal.

TagTitle / Link
BrainA 3-Month Aerobic Training Program Improves Brain Energy Metabolism in Mild Alzheimer's Disease: Preliminary Results from a Neuroimaging Study
DietA bacterial homolog of a eukaryotic inositol phosphate signaling enzyme mediates cross-kingdom dialog in the mammalian gut
DiabetesA comparative study of thyroid hormone levels in diabetic and non-diabetic patients
AtherosclerosisA comprehensive classification system for lipids.
ExerciseA computational model of skeletal muscle metabolism linking cellular adaptations induced by altered loading states to metabolic responses during exercise.
EpigeneticsA critical view on transgenerational epigenetic inheritance in humans
BrainA cross-sectional comparison of brain glucose and ketone metabolism in cognitively healthy older adults, mild cognitive impairment and early Alzheimer's disease.
EnvironmentA Dose-Response Curve Describing the Relationship Between Urban Tree Cover Density and Self-Reported Stress Recovery
DietA High Fiber Cookie Made with Resistant Starch Type 4 Reduces Post-Prandial Glucose and Insulin Responses in Healthy Adults
AtherosclerosisA lipidomic analysis of nonalcoholic fatty liver disease.
MitochondriaA Mitochondrial Bioenergetic Etiology of Disease
ExerciseA Mutation in the Myostatin Gene Increases Muscle Mass and Enhances Racing Performance in Heterozygote Dogs
DietA periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance and healthspan
ObesityA pilot study: does obesity begin in the first year of life?
ExerciseA randomized controlled trial on the effectiveness of 8-week high-intensity interval exercise on intrahepatic triglycerides, visceral lipids, and health-related quality of life in diabetic obese patients with nonalcoholic fatty liver disease.
DietA review of pomegranate in prostate cancer
DietA short-term, high-fat diet up-regulates lipid metabolism and gene expression in human skeletal muscle
DietAdding monounsaturated fatty acids to a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia
CancerAdipose tissue trans fatty acids and breast cancer in the European Community Multicenter Study on Antioxidants, Myocardial Infarction, and Breast Cancer
ObesityAdolescent obesity and puberty: the "perfect storm"
SmokingAdvanced glycation endproducts and cigarette smoking
AgingAge and energy intake interact to modify cell stress pathways and stroke outcome.
AgingAgeing and neuronal vulnerability.
DietAgrarian diet and diseases of affluence‚ Do evolutionary novel dietary lectins cause leptin resistance?
DietAgrp neuron activity is required for alcohol-induced overeating
AtherosclerosisAlbany Cardiovascular Health Study
AlcoholAlcohol Metabolism and Epigenetics Changes
AlcoholAlcoholic ketoacidosis
AtherosclerosisAlirocumab Treatment and Achievement of Non-High-Density Lipoprotein Cholesterol and Apolipoprotein B Goals in Patients With Hypercholesterolemia: Pooled Results From 10 Phase 3 ODYSSEY Trials.
Dietalpha-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans
DietAlternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma.
StressAltruism, happiness, and health: it's good to be good
AtherosclerosisAlzheimer's Disease: Brain Desmosterol Levels
mTORAmino acids and mTORC1: from lysosomes to disease
ExerciseAn acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle
AtherosclerosisAn assessment by the Statin Cognitive Safety Task Force: 2014 update.
AtherosclerosisAn assessment by the Statin Liver Safety Task Force: 2014 update.
AtherosclerosisAn assessment by the Statin Muscle Safety Task Force: 2014 update.
NAFLDAn assessment of bacterial overgrowth and translocation in the non-alcoholic fatty liver of patients with morbid obesity.
ExerciseAn integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training.
DietAn Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity
AtherosclerosisAnti-inflammatory therapies for cardiovascular disease.
AtherosclerosisAntiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
AtherosclerosisApolipoprotein B and cardiovascular disease risk: position statement from the AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices.
AtherosclerosisApolipoprotein C-III is Significantly Reduced by Prescription Omega-3 Free Fatty Acids (Epanova) in Patients with Severe Hypertriglyceridemia and Changes Correlate with Increases in LDL-C: A Sub-analysis of the EVOLVE trial
AtherosclerosisApolipoprotein E-containing high-density lipoprotein (HDL) modifies the impact of cholesterol-overloaded HDL on incident coronary heart disease risk: A community-based cohort study.
AtherosclerosisApolipoprotein structure and dynamics.
ExerciseAppetite regulation in response to sitting and energy imbalance
DietArthritis associated with gluten-sensitive enteropathy
ObesityAssessing the fetal effects of maternal obesity via transcriptomic analysis of cord blood: a prospective case-control study
BrainAssociation Between Mitochondrial DNA Haplogroup Variation and Autism Spectrum Disorders
Vitamin DAssociation between serum vitamin D and metabolic syndrome in middle-aged and older adults and role of supplementation therapy with vitamin D
AtherosclerosisAssociation of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease.
Atherosclerosisat Transport in Lipoproteins ‚ An Integrated Approach to Mechanisms and Disorders
ObesityAutonomic dysfunction of the beta-cell and the pathogenesis of obesity
NAFLDBariatric and metabolic endoscopy in the handling of fatty liver disease. A new emerging approach?
ExerciseBDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1.
AtherosclerosisBeneficial Effects of Combined Colestipol-Niacin Therapy on Coronary Atherosclerosis and Coronary Venous Bypass Grafts
Insulinβ-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle.
NAFLDBile acid alterations in nonalcoholic fatty liver disease, obesity, insulin resistance and type 2 diabetes: what do the human studies tell?
DietBiological activities of curcuminoids, other biomolecules from turmeric and their derivatives - A review
AtherosclerosisBiomarkers of cholesterol homeostasis in a clinical laboratory database sample comprising 667,718 patients.
NAFLDBookshelf: Fatty Liver
ExerciseBorn to run; the story of the PEPCK-Cmus mouse*
BrainBrain glucose and acetoacetate metabolism: a comparison of young and older adults
Diet BrainBrain-Gut-Microbiota Axis in Alzheimer's Disease
DietBrain-gut-microbiota axis in Parkinson's disease.
DietCaloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease.
DietCarbohydrate intake and cardiometabolic risk factors in high BMI African American children
ExerciseCardiorespiratory Fitness and Classification of Risk of Cardiovascular Disease Mortality
DietChanges in Dietary Fat Intake Alter Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a)
ObesityChanges in energy expenditure resulting from altered body weight.
DietChanges in USDA food composition data for 43 garden crops, 1950 to 1999.
InsulinChanging the Way We Think About Endothelial Cell Insulin Sensitivity, Nitric Oxide, and the Pathophysiology of Type 2 Diabetes
AtherosclerosisCharacterization of two high-density lipoprotein binding sites on porcine hepatocyte plasma membranes: contribution of scavenger receptor class B type I (SR-BI) to the low-affinity component.
EnvironmentChildhood exposure to green space - A novel risk-decreasing mechanism for schizophrenia?
ObesityChildhood obesity.
ObesityChildhood obesity: behavioral aberration or biochemical drive? Reinterpreting the First Law of Thermodynamics.
AtherosclerosisCholesterol and plant sterol absorption: recent insights.
AtherosclerosisCholesterol: the debate should be terminated.
DietChronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway
DietChronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
SmokingCigarette smoking and DNA methylation
DiabetesCinnamaldehyde in diabetes: A review of pharmacology, pharmacokinetics and safety
DietCircadian rhythms, time-restricted feeding, and healthy aging.
AtherosclerosisClinical and pathophysiological evidence supporting the safety of extremely low LDL levels-The zero-LDL hypothesis.
DietCoca Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
BrainCognitive performance is improved while walking: Differences in cognitive‚ sensorimotor couplings between children and young adults
AtherosclerosisColchicine Cardiovascular Outcomes Trial (COLCOT) (COLCOT)
ExerciseComparative study of millennials' (age 20-34 years) grip and lateral pinch with the norms.
AtherosclerosisComparison of a novel method vs the Friedewald equation for estimating low-density lipoprotein cholesterol levels from the standard lipid profile.
DietComparison of low fat and low carbohydrate diets on circulating fatty acid composition and markers of inflammation
DietComparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity
DietConjugated linoleic acid: A potent fatty acid linked to animal and human health
DietConsumption of whole eggs promotes greater stimulation of postexercise muscle protein synthesis than consumption of isonitrogenous amounts of egg whites in young men.
InsulinContribution of hyperinsulinemia to modulation of lipoprotein lipase activity in the obese Zucker rat
AtherosclerosisCoronary atherosclerosis status of MER-29 (triparanol).
AtherosclerosisCoronary heart disease in patients with low LDL-cholesterol: benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors.
AtherosclerosisCoronary heart disease risks associated with high levels of HDL cholesterol.
DietCranberries inhibit LDL oxidation and induce LDL receptor expression in hepatocytes
SocietyCrowding Among Hunter-Gatherers: The !Kung Bushmen
DietCruciferous Vegetable Intake Is Inversely Associated with Lung Cancer Risk among Current Nonsmoking Men in the Japan Public Health Center (JPHC) Study
AtherosclerosisCrystallopathies
DietCytotoxicity and genotoxicity of lipid-oxidation products
AuthorsDavid Sabatini Lab Publication Page @ Whitehead
DietDecreased levels of heat shock proteins in gut epithelial cells after exposure to plant lectins
AtherosclerosisDeficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.
AtherosclerosisDevelopment of a proton nuclear magnetic resonance spectroscopic method for determining plasma lipoprotein concentrations and subspecies distributions from a single, rapid measurement.
DietDiabetes and dietary fibre: directive or distraction?
BrainDiabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons.
AtherosclerosisDiabetic Retinopathy, Its Progression, and Incident Cardiovascular Events in the ACCORD Trial
AtherosclerosisDiagnosis of type III hyperlipoproteinemia from plasma total cholesterol, triglyceride, and apolipoprotein B
DietDietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal.
AtherosclerosisDietary Fat and Its Relation to Heart Attacks and Strokes
DietDietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women.
DietDietary intake associated with serum versus urinary carboxymethyl-lysine, a major advanced glycation end product, in adults: the Energetics Study
DietDietary modifications in atopic dermatitis: patient-reported outcomes
DietDietary Reference Intakes for Calcium and Vitamin D
DietDietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice.
DietDietary treatment of nonalcoholic steatohepatitis
DietDiet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats.
ExerciseDihydrotestosterone is elevated following sprint exercise in healthy young men
BrainDirect Transcriptional Effects of Apolipoprotein E.
StressDisclosing information about the self is intrinsically rewarding
AtherosclerosisDiscordance analysis and the Gordian Knot of LDL and non-HDL cholesterol versus apoB.
AtherosclerosisDiscovery of the Lipoproteins, Their Role in Fat Transport and Their Significance as Risk Factors
AtherosclerosisDistribution of triglyceride and total, LDL and HDL cholesterol in several populations: A cooperative lipoprotein phenotyping study
AtherosclerosisDistribution of triglyceride and total, LDL and HDL cholesterol in several populations: a cooperative lipoprotein phenotyping study.
DietDo dietary lectins cause disease?
DietDoes moderate alcohol consumption affect fertility? Follow up study among couples planning first pregnancy
DietDose-dependent responses of myofibrillar protein synthesis with beef ingestion are enhanced with resistance exercise in middle-aged men
AtherosclerosisDrug safety evaluation of rosuvastatin.
StressEarly Life Conditions and Physiological Stress following the Transition to Farming in Central/Southeast Europe: Skeletal Growth Impairment and 6000 Years of Gradual Recovery
AtherosclerosisEffect of Darapladib on Major Coronary Events After an Acute Coronary Syndrome
AtherosclerosisEffect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): a prespeciԨŠed analysis of a randomised controlled trial
AtherosclerosisEffect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial.
AtherosclerosisEffect of fenofibrate on uric acid and gout in type 2 diabetes: a post-hoc analysis of the randomised, controlled FIELD study - The Lancet Diabetes & Endocrinology
MaternityEffect of Gestational Diabetes and Maternal Obesity on Fetal Programming
DietEffect of marinades on the formation of heterocyclic amines in grilled beef steaks
InflammationEffect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages
DietEffects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial.
AtherosclerosisEffects of Anacetrapib in Patients with Atherosclerotic Vascular Disease.
SunlightEffects of artificial light at night on human health: A literature review of observational and experimental studies applied to exposure assessment
AtherosclerosisEffects of combination lipid therapy in type 2 diabetes mellitus.
AtherosclerosisEffects of dalcetrapib in patients with a recent acute coronary syndrome.
DietEffects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance
FructoseEffects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity.
AtherosclerosisEffects of Evolocumab on Vitamin E and Steroid Hormone Levels: Results From the 52-Week, Phase 3, Double-Blind, Randomized, Placebo-Controlled DESCARTES Study.
ExerciseEffects of Exercise on Mitochondrial Content and Function in Aging Human Skeletal Muscle
ExerciseEffects of exercise training on mitochondrial function in patients with type 2 diabetes
AtherosclerosisEffects of Extended-Release Niacin with Laropiprant in High-Risk Patients
AtherosclerosisEffects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study
AtherosclerosisEffects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance.
DietEffects of leucine and its metabolite β‐hydroxy‐β‐methylbutyrate on human skeletal muscle protein metabolism
DietEffects of meals high in carbohydrate, protein, and fat on ghrelin and peptide YY secretion in prepubertal children
AtherosclerosisEffects of omega-3 carboxylic acids on lipoprotein particles and other cardiovascular risk markers in high-risk statin-treated patients with residual hypertriglyceridemia: a randomized, controlled, double-blind trial.
DietEffects of Popular Diets without Specific Calorie Targets on Weight Loss Outcomes: Systematic Review of Findings from Clinical Trials
AtherosclerosisEffects of raloxifene on cardiovascular events and breast cancer in postmenopausal women.
DietEffects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome
ObesityEffects of systemic growth hormone (GH) administration on regional adipose tissue in children with non-GH-deficient short stature.
AtherosclerosisEffects of the Selective Estrogen Receptor Modulator Raloxifene on Coronary Outcomes in The Raloxifene Use for the Heart Trial
DietEffects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction
AtherosclerosisEfficacy of Ezetimibe for the Treatment of Non-Alcoholic Fatty Liver Disease: A Randomized, Controlled Trial
EndochrinologyEmerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule.
BrainEnergetic and nutritional constraints on infant brain development: implications for brain expansion during human evolution.
BrainEnergy intake and exercise as determinants of brain health and vulnerability to injury and disease.
EpigeneticsEpigenetic diet: impact on the epigenome and cancer
EpigeneticsEpigenetic Inheritance: Concepts, Mechanisms and Perspectives
MaternityEpigenetic Mechanisms Link Maternal Diets and Gut Microbiome to Obesity in the Offspring
MaternityEpigenetic signatures of gestational diabetes mellitus on cord blood methylation
ExerciseEpigenetics in Exercise Science and Sports Medicine
AtherosclerosisEstimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.
AlcoholEthanol Alters Energy Metabolism in the Liver
DietEthanol does not delay muscle recovery but decreases testosterone/cortisol ratio
AtherosclerosisEvans County cardiovascular and cerebrovascular study.
AtherosclerosisEvolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
DietExposure of infants to phyto-oestrogens from soy-based infant formula
SunlightExtraocular circadian phototransduction in humans
AtherosclerosisEzetimibe therapy: mechanism of action and clinical update
MaternityFactors that affect maternal insulin resistance and modify fetal growth and body composition.
DietFailed Recovery of Glycemic Control and Myofibrillar Protein Synthesis With 2 wk of Physical Inactivity in Overweight, Prediabetic Older Adults
AlcoholFalse-positive breath-alcohol test after a ketogenic diet
ObesityFast food, central nervous system insulin resistance, and obesity.
DietFasting and Caloric Restriction in Cancer Prevention and Treatment
DietFasting: molecular mechanisms and clinical applications.
DietFasting-Mimicking Diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease
DietFasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes
AtherosclerosisFatty Acids: Structures and Properties
AtherosclerosisFenofibrate-associated changes in renal function and relationship to clinical outcomes among individuals with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) experience.
MaternityFetal gender and maternal insulin resistance during mid-pregnancy
AtherosclerosisFibrate therapy in patients with metabolic syndrome and diabetes mellitus
AtherosclerosisFifty years of advances in bile acid synthesis and metabolism.
DietFlipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
DietFood restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults.
EnvironmentForest bathing enhances human natural killer activity and expression of anti-cancer proteins
BrainFrequency-modulated 50kHz ultrasonic vocalizations: a tool for uncovering the molecular substrates of positive affect
NAFLDFructose consumption as a risk factor for non-alcoholic fatty liver disease.
FructoseFructose: it's "alcohol without the buzz".
DietFruit and Soil Quality of Organic and Conventional Strawberry Agroecosystems
AtherosclerosisGemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group.
ExerciseGenome-wide association study identifies three novel genetic markers associated with elite endurance performance
ExerciseGive your ideas some legs: the positive effect of walking on creative thinking
BrainGLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.
EnvironmentGreen spaces and cognitive development in primary schoolchildren
DietGreen tea catechins and cardiovascular health: an update
mTORGrowing roles for the mTOR pathway
Diet BrainGut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.
DietHallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.
AtherosclerosisHDL and cardiovascular disease
AtherosclerosisHDL cholesterol/HDL particle ratio: a new measure of HDL function?
NAFLDHealth and economic benefits of reducing sugar intake in the USA, including effects via non-alcoholic fatty liver disease: a microsimulation model.
EnvironmentHealth Benefits from Nature Experiences Depend on Dose
DietHealth benefits of docosahexaenoic acid (DHA)
AtherosclerosisHelsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease.
AtherosclerosisHepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis.
LiverHepatic steatosis after pediatric liver transplant.
DietHigh consumption of salt-fermented vegetables and hypertension risk in adults: a 12-year follow-up study
AtherosclerosisHigh-density lipoproteins: a consensus statement from the National Lipid Association.
AtherosclerosisHigh-density lipoproteins: emerging knowledge.
AtherosclerosisHigh-Density Lipoproteins: Structure, Metabolism, Function, and Therapeutics
DietHistorical changes in the mineral content of fruits and vegetables
HormesisHormesis defined.
AtherosclerosisHPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment
InsulinHyperinsulinemia causes activation of the hypothalamus-pituitary-adrenal axis in humans
InsulinHyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults
AtherosclerosisHypocholesterolemia, foam cell accumulation, but no atherosclerosis in mice lacking ABC-transporter A1 and scavenger receptor BI.
BrainHypothalamic dysfunction after chemotherapy.
BrainHypothalamic obesity caused by cranial insult in children: altered glucose and insulin dynamics and reversal by a somatostatin agonist.
BrainHypothalamic obesity: causes, consequences, treatment
AtherosclerosisIdentification of a new plasma biomarker of Alzheimer's disease using metabolomics technology
SleepImpact of acute sleep restriction on cortisol and leptin levels in young women
AtherosclerosisImpact of phospholipid transfer protein on nascent high-density lipoprotein formation and remodeling.
DietImpact of phytic acid on nutrient bioaccessibility and antioxidant properties of dehusked rice
AtherosclerosisImpact on cognitive function-are all statins the same?
AtherosclerosisInactivating mutations in NPC1L1 and protection from coronary heart disease.
AtherosclerosisInborn errors of cholesterol biosynthesis.
MaternityIncreased maternal insulin resistance promotes placental growth and decreases placental efficiency in pregnancies with obesity and gestational diabetes mellitus.
ExerciseIncreased p70s6k phosphorylation during intake of a protein-carbohydrate drink following resistance exercise in the fasted state
NAFLDIndependent markers of non-alcoholic fatty liver disease in a gentrifying population based Chinese cohort.
NAFLDInnate immune regulatory networks in hepatic lipid metabolism.
InsulinInsulin dynamics predict body mass index and z-score response to insulin suppression or sensitization pharmacotherapy in obese children.
DietInsulin levels, hunger, and food intake: an example of feedback loops in body weight regulation
InsulinInsulin meets its receptor
InsulinInsulin, Insulin Resistance, and Platelet Signaling in Diabetes
InsulinInsulin-Induced Hypoglycemia as a Test of Pituitary-Adrenal Function in Thyrotoxicosis
AtherosclerosisIntensive lipid lowering with simvastatin and ezetimibe in aortic stenosis.
AtherosclerosisInteraction between sphingomyelin and oxysterols contributes to atherosclerosis and sudden death
AtherosclerosisInteractions of oxysterols with membranes and proteins.
AtherosclerosisIntestinal lipid absorption.
AtherosclerosisIntrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice.
BrainInverse relationship between brain glucose and ketone metabolism in adults during short-term moderate dietary ketosis: A dual tracer quantitative positron emission tomography study
BrainInvolvement of PGC-1α in the formation and maintenance of neuronal dendritic spines.
FructoseIsocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome.
AtherosclerosisLDL Particle Number and Risk of Future Cardiovascular Disease in the Framingham Offspring Study - Implications for LDL Management.
AtherosclerosisLectins, agglutinins, and their roles in autoimmune reactivities
AuthorsLeibel, RL
LeptinLeptin
BrainLifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence.
AtherosclerosisLipid landscapes and pipelines in membrane homeostasis.
AtherosclerosisLipid lowering with PCSK9 inhibitors
AtherosclerosisLipoprotein lipase: from gene to atherosclerosis.
AtherosclerosisLipoprotein retention--and clues for atheroma regression.
AtherosclerosisLipoprotein(a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptor.
AgingLongevity Among Hunter-Gatherers: A Cross-Cultural Examination
AtherosclerosisLong-term effects of fenofibrate on VLDL and HDL subspecies in participants with type 2 diabetes mellitus
AtherosclerosisLong-Term Safety and Efficacy of Lowering Low-Density Lipoprotein Cholesterol With Statin Therapy: 20-Year Follow-Up of West of Scotland Coronary Prevention Study.
AtherosclerosisLow density lipoprotein oxidation, antioxidants, and atherosclerosis
AtherosclerosisLow LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.
BrainLower Brain 18F-Fluorodeoxyglucose Uptake But Normal 11C-Acetoacetate Metabolism in Mild Alzheimer's Disease Dementia
AuthorsLustig, RH
DietLutein and Zeaxanthin-Food Sources, Bioavailability and Dietary Variety in Age-Related Macular Degeneration Protection
DietMacronutrient intakes and cardio metabolic risk factors in high BMI African American children.
EpigeneticsMaternal Epigenetic Inheritance and Stress During Gestation: Focus on Brain and Behavioral Disorders
MaternityMaternal inheritance of human mitochondrial DNA
MaternityMaternal Insulin Resistance and Preeclampsia
MaternityMaternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring
DietMaternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring
MaternityMaternal obesity and fetal metabolic programming: a fertile epigenetic soil
MaternityMaternal Obesity Induces Epigenetic Modifications to Facilitate Zfp423 Expression and Enhance Adipogenic Differentiation in Fetal Mice
MaternityMaternal overnutrition programs epigenetic changes in the regulatory regions of hypothalamic Pomc in the offspring of rats
MaternityMaternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications
DietMeal frequency and timing in health and disease.
AtherosclerosisMechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism
AtherosclerosisMER-29 (Triparanol) in the Control of Hypercholesterolæmia
DietMeta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease
ExerciseMetabolic characteristics of keto-adapted ultra-endurance runners
NAFLDMetabolic characterization of two different non-alcoholic fatty liver disease pre-clinical mouse models.
Diet BrainMetabolic profiling distinguishes three subtypes of Alzheimer's disease
SleepMetabolic, Endocrine, and Immune Consequences of Sleep Deprivation
AtherosclerosisMethotrexate and Cardiovascular Protection: Current Evidence and Future Directions
DietMfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.
BrainMind-controlled transgene expression by a wireless-powered optogenetic designer cell implant
DietMindfulness Intervention for Stress Eating to Reduce Cortisol and Abdominal Fat among Overweight and Obese Women: An Exploratory Randomized Controlled Study.
DietMineral nutrient composition of vegetables, fruits and grains: The context of reports of apparent historical declines
MitochondriaMitochondrial DNA Mutation Associated with Leber's Hereditary Optic Neuropathy
MitochondriaMitochondrial DNA Variation in Human Radiation and Disease
AgingMitochondrial enzyme activities as biochemical markers of aging
MitochondriaMitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.
BrainMitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise, and Metabolic and Excitatory Challenges
ExerciseMixed muscle protein synthesis and breakdown after resistance exercise in humans
DietModified Egg Composition To Reduce Low-Density Lipoprotein Oxidizability: High Monounsaturated Fatty Acids and Antioxidants versus Regular High n‚àí6 Polyunsaturated Fatty Acids
InflammationMolecular Inflammation: Underpinnings of Aging and Agerelated Diseases
AtherosclerosisMolecular Mechanisms of Cellular Cholesterol Efflux*
LipidologyMolecular mechanisms regulating hormone-sensitive lipase and lipolysis
EpigeneticsMother knows best: Epigenetic inheritance, maternal effects, and the evolution of human intelligence
mTORmTOR is a key modulator of ageing and age-related disease
mTORmTOR Signaling in Growth Control and Disease
ExerciseMulti-organ system model of O2 and CO2 transport during isocapnic and poikilocapnic hypoxia.
ExerciseMuscle Disuse as a Pivotal Problem in Sarcopenia-related Muscle Loss and Dysfunction
ExerciseMuscle-Strengthening Exercise Among 397,423 U.S. Adults: Prevalence, Correlates, and Associations With Health Conditions
AtherosclerosisMutations in PCSK9 cause autosomal dominant hypercholesterolemia.
AtherosclerosisMutations in the 3β-Hydroxysterol Δ24-Reductase Gene Cause Desmosterolosis, an Autosomal Recessive Disorder of Cholesterol Biosynthesis
BrainNGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis.
AtherosclerosisNiacin in patients with low HDL cholesterol levels receiving intensive statin therapy.
SunlightNocturnal light pollution and underexposure to daytime sunlight: Complementary mechanisms of circadian disruption and related diseases
NAFLDNon-alcoholic fatty liver disease
NAFLDNon-alcoholic Fatty Liver Disease: A Clinical Update
NAFLDNon-alcoholic fatty liver disease: An expanded review
NAFLDNon-alcoholic fatty liver disease: an update on diagnosis
NAFLDNon-alcoholic fatty pancreas disease - practices for clinicians
DietNon-coeliac gluten sensitivity and reproductive disorders
AtherosclerosisNon-invited Review: Prevention of microvascular diabetic complications by fenofibrate: lessons from FIELD and ACCORD
InflammationNon-steroidal anti-inflammatory drugs and gastrointestinal damage‚ problems and solutions
MaternityNovel Interventions to Reduce Stress and Overeating in Overweight Pregnant Women: A Feasibility Study.
AtherosclerosisNuclear receptor signaling in the control of cholesterol homeostasis: have the orphans found a home?
DietNutritional armor in evolution: docosahexaenoic acid as a determinant of neural, evolution and hominid brain development
DietNutritional comparison of fresh, frozen, and canned fruits and vegetables II. Vitamin A and carotenoids, vitamin E, minerals and fiber
EpigeneticsNutritional Implications of Epigenetics and Metabolic Syndrome
ObesityObesity in childhood.
InsulinObesity, leptin resistance, and the effects of insulin reduction
ObesityObesity, leptin resistance, and the effects of insulin reduction.
BrainOctreotide therapy of pediatric hypothalamic obesity: a double-blind, placebo-controlled trial
AgingOlder age becomes common late in human evolution
AtherosclerosisOmega-3 free fatty acids for the treatment of severe hypertriglyceridemia: the EpanoVa fOr Lowering Very high triglyceridEs (EVOLVE) trial.
AtherosclerosisOptimization of β-Quantification Methods for High-Throughput Applications
DietOrigins and evolution of the Western diet: health implications for the 21st century
ExerciseOverexpression of the Cytosolic Form of Phosphoenolpyruvate Carboxykinase (GTP) in Skeletal Muscle Repatterns Energy Metabolism in the Mouse
MaternityOverview of Pup in a Cup Model: Hepatic Lipogenesis in Rats Artificially Reared on a High-Carbohydrate Formula
AtherosclerosisOxidation of Linoleic Acid in Low\u2010Density Lipoprotein: An Important Event in Atherogenesis
ObesityPathophysiology of childhood obesity.
BrainPathways towards and away from Alzheimer's disease.
ObesityPatient guide to the prevention and management of pediatric obesity.
BrainPediatric endocrine disorders of energy balance.
AtherosclerosisPetar Alaupovic: The father of lipoprotein classification based on apolipoprotein composition.
AtherosclerosisPfizer stops clinical trials of heart drug
ExercisePGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity
DietPhytate degradation by human gut isolated Bifidobacterium pseudocatenulatum ATCC27919 and its probiotic potential
BrainPituitary development and physiology.
InflammationPlacebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence
AtherosclerosisPlant sterols, cholesterol precursors and oxysterols: Minute concentrations-Major physiological effects.
AtherosclerosisPlant Sterols, Stanols, and Sitosterolemia
DietPlant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets.
ExercisePractical aspects of indirect calorimetry in laboratory animals.
NAFLDPrevalence of diabetes in liver cirrhosis: A systematic review and meta-analysis.
ObesityPrevention and treatment of pediatric obesity: an endocrine society clinical practice guideline based on expert opinion.
AtherosclerosisPrevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group.
ExercisePrimum non nocere: A commentary on avoidable injuries and safe resistance training techniques
DietProblems associated with glucose toxicity: Role of hyperglycemia-induced oxidative stress
AtherosclerosisProbucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group.
DietProduction and application of menaquinone-7 (vitamin K2): a new perspective
SunlightProopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis.
DietProtein ingestion before sleep improves postexercise overnight recovery.
stressPsychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry
DietPublic health: The toxic truth about sugar.
InsulinRace affects insulin and GLP-1 secretion and response to a long-acting somatostatin analogue in obese adults.
ObesityRacial and etiopathologic dichotomies in insulin hypersecretion and resistance in obese children.
InsulinRacial differences in glucagon-like peptide-1 (GLP-1) concentrations and insulin dynamics during oral glucose tolerance test in obese subjects
InflammationRacial disparity in glucagon-like peptide 1 and inflammation markers among severely obese adolescents.
mTORRAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
AtherosclerosisRandomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
DietRandomized cross-over trial of short-term water-only fasting: metabolic and cardiovascular consequences
mTORRapalogs and mTOR inhibitors as anti-aging therapeutics
ObesityRecent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity
AtherosclerosisReceptor-Mediated Control of Cholesterol Metabolism
AgingRecruiting adaptive cellular stress responses for successful brain ageing.
AtherosclerosisRediscovering scavenger receptor type BI: surprising new roles for the HDL receptor.
GlycationReduced formation of advanced glycation endproducts via interactions between glutathione peroxidase 3 and dihydroxyacetone kinase 1
DietReduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss: Data from the SHINE randomized controlled trial.
AtherosclerosisRegression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B.
mTORRegulation of mTORC1 by amino acids
DietRegulation of Vitamin C Transport
DietRelation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men
ExerciseRelationships between testosterone, cortisol and performance in professional cyclists
EnvironmentResidential green space in childhood is associated with lower risk of psychiatric disorders from adolescence into adulthood
ExerciseResistance Exercise Reverses Aging in Human Skeletal Muscle
SunlightResponse of the Human Circadian System to Millisecond Flashes of Light
BrainReversal of cognitive decline: A novel therapeutic program
AtherosclerosisReverse cholesterol transport fluxes.
ObesityRisk factors for the development of obesity in children surviving brain tumors
DietRobert Lustig: The no candy man
InflammationRole of commensal gut bacteria in inflammatory bowel diseases¬
AtherosclerosisRole of fibrates in cardiovascular disease prevention, the ACCORD-Lipid perspective.
LeptinRole of leptin in energy homeostasis in humans
AtherosclerosisRole of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
DietRole of n-3 Polyunsaturated Fatty Acids in Ameliorating the Obesity-Induced Metabolic Syndrome in Animal Models and Humans
ExerciseRowers' high: behavioural synchrony is correlated with elevated pain thresholds
AtherosclerosisRussell Ross 2016 Memorial Lecture in Vascular Biology: Molecular-Cellular Mechanisms in the Progression of Atherosclerosis.
NAFLDSarcopenic obesity in fatty liver.
DietSeafood Consumption and Components for Health
AtherosclerosisSeeking a Unique Lipid Signature Predicting Cardiovascular Disease Risk
DietSelenium as an antidote in the treatment of mercury intoxication
AtherosclerosisSerum plant sterols as a potential risk factor for coronary heart disease.
InflammationShort-chain fatty acid in the human colon. Relation to inflammatory bowel diseases and colon cancer
AtherosclerosisSimvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease.
SleepSleep and immune function
SleepSleep, Sleepiness, and Alcohol Use
AtherosclerosisSmith-Lemli-Opitz Syndrome in a newborn infant with developmental abnormalities and low endogenous cholesterol
SocietySocioeconomic status in relation to early menarche among black and white girls.
AtherosclerosisSpeciated High-Density Lipoprotein Biogenesis and Functionality.
ExerciseSprint interval running increases insulin sensitivity in young healthy subjects
ExerciseSprint-based exercise and cognitive function in adolescents
ExerciseStand up for health--avoiding sedentary behaviour might lengthen your telomeres: secondary outcomes from a physical activity RCT in older people
AtherosclerosisStatin Therapy Is Associated With Lower Total but Not Bioavailable or Free Testosterone in Men With Type 2 Diabetes
AtherosclerosisStatins in the treatment of dyslipidemia in the presence of elevated liver aminotransferase levels: a therapeutic dilemma.
AtherosclerosisSteroidal triterpenes of cholesterol synthesis.
StressStress and Disease
StressStress and the neuroendocrine system: the role of exercise as a stressor and modifier of stress
StressStress, Endocrine Physiology and Pathophysiology
AtherosclerosisStructure of human serum lipoproteins inferred from compositional analysis.
ObesitySugar-sweetened beverages, serum uric acid, and blood pressure in adolescents.
DietSuppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults
SleepSynapse remodeling during sleep
ObesityTelevision viewing and hypertension in obese children.
InsulinTG/HDL ratio as surrogate marker for insulin resistance
AtherosclerosisThe biology of PCSK9 inhibition: Some unanswered questions
NAFLDThe clinical effects of purslane (Portulaca oleracea) seeds on metabolic profiles in patients with nonalcoholic fatty liver disease: A randomized controlled clinical trial.
GlycationThe clinical relevance of assessing advanced glycation endproducts accumulation in diabetes
NAFLDThe Correlation of Neck Circumference and Insulin Resistance in NAFLD Patients.
SocietyThe Cost of Obesity for Nonbariatric Inpatient Operative Procedures in the United States: National Cost Estimates Obese versus Nonobese Patients
DietThe critical role played by animal source foods in human (Homo) evolution
InflammationThe Effect of Abdominal Visceral Fat, Circulating Inflammatory Cytokines, and Leptin Levels on Reflux Esophagitis
ExerciseThe effect of lower limb length on the energetic cost of locomotion: implications for fossil hominins
AtherosclerosisThe effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators.
ExerciseThe effectiveness of manual stretching in the treatment of plantar heel pain: a systematic review
EnvironmentThe effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune disease
ExerciseThe effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women.
AtherosclerosisThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
InsulinThe effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes.
StressThe effects of surfing and the natural environment on the well-being of combat veterans
StressThe effects of tea on psychophysiological stress responsivity and post-stress recovery: a randomised double-blind trial
EpigeneticsThe Epigenetics of Sex Differences in the Brain
ObesityThe first months of life: a critical period for development of obesity
AtherosclerosisThe Framingham Heart Study
AtherosclerosisThe Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective
AtherosclerosisThe Honolulu Heart Study
SleepThe Impact of Daily Sleep Duration on Health: A Review of the Literature
SleepThe impact of sleep deprivation on food desire in the human brain
DietThe impact of sugar sweetened beverage intake on hunger and satiety in minority adolescents
DietThe importance of the ratio of omega-6/omega-3 essential fatty acids
InflammationThe inflammation theory of disease
ExerciseThe influence of sprint interval training on body composition, physical and metabolic fitness in adolescents and young adults with intellectual disabilities
AtherosclerosisThe Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease.
AtherosclerosisThe MER/29 Story--An Instance of Succesful Mass Disaster Litigation
SleepThe Metabolic Consequences of Sleep Deprivation
DietThe Microbiome in Mental Health: Potential Contribution of Gut Microbiota in Disease and Pharmacotherapy Management
mTorThe mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulation.
AtherosclerosisThe Multiple Risk Factor Intervention Trial (MRFIT)--importance then and now.
AtherosclerosisThe myth of statin-induced hepatotoxicity.
DietThe Neanderthal Meal: A New Perspective Using Faecal Biomarkers
BrainThe neuroendocrinology of childhood obesity.
ObesityThe neuroendocrinology of obesity.
AtherosclerosisThe pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part IV: the 1984 coronary primary prevention trial ends it--almost.
AtherosclerosisThe Puerto Rico Heart Study
DietThe role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis.
NAFLDThe role of fructose in the pathogenesis of NAFLD and the metabolic syndrome.
DietThe role of intestinal microbiota in the pathogenesis of metabolic diseases
AtherosclerosisThe role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis.
NAFLDThe role of Small Intestinal Bacterial Overgrowth (SIBO) in Non-alcoholic Fatty Liver Disease (NAFLD) patients evaluated using Controlled Attenuation Parameter (CAP) Transient Elastography (TE): a tertiary referral center experience.
AtherosclerosisThe Search for a High Sensitivity Creatinine Assay
BrainThe 'skinny' on childhood obesity: how our western environment starves kids' brains.
AtherosclerosisThe structure and function of Niemann-Pick C1-like 1 protein.
SunlightThe Sunny Side of Addiction
mTORThe TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span.
AtherosclerosisThematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part V: the discovery of the statins and the end of the controversy.
AtherosclerosisThematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy: part II: the early evidence linking hypercholesterolemia to coronary disease in humans.
AtherosclerosisThematic review series: the pathogenesis of atherosclerosis: an interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemia.
AtherosclerosisTherapeutic Lipidology
ExerciseThree 15-min Bouts of Moderate Postmeal Walking Significantly Improves 24-h Glycemic Control in Older People at Risk for Impaired Glucose Tolerance
AtherosclerosisTietz Textbook of Clinical Chemistry and Molecular Diagnostics,6th Edition
DietTight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms
DietTime-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock
ExerciseToo Much Sitting: The Population-Health Science of Sedentary Behavior
Vitamin DTotal and free circulating vitamin D and vitamin D binding protein in relation to colorectal cancer risk in a prospective study of African Americans
ExerciseTowards ageing well: Use it or lose it: Exercise, epigenetics and cognition
SunlightToxicity and Phototoxicity of Chemical Sun Filters
DietTrans Fats Judged Major Villain in Cardiovascular Disease
DietTrans fats‚ sources, health risks and alternative approach - A review
DietTrans fatty acids‚ effects on systemic inflammation and endothelial function
EpigeneticsTransgenerational epigenetic inheritance in mammals: how good is the evidence?
EpigeneticsTransgenerational Epigenetic Inheritance: myths and mechanisms
PaternityTransgenerational inheritance of susceptibility to diabetes-induced male subfertility
StressTransgenerational transmission of cortisol and PTSD risk
BrainTumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.
BrainTumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis.
Vitamin DTumor suppression in skin and other tissues via cross-talk between vitamin D- and p53-signaling
Leptin20 years of leptin: role of leptin in energy homeostasis in humans.
mTORTwenty-five years of mTOR: Uncovering the link from nutrients to growth
ExerciseTwo weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women
AtherosclerosisUltracentrifugal studies of lipoproteins of human serum.
AtherosclerosisUnbound free fatty acid levels in human serum.
AtherosclerosisUnderstanding high-density lipoprotein function in disease: recent advances in proteomics unravel the complexity of its composition and biology.
AtherosclerosisUpdate of the LIPID MAPS comprehensive classification system for lipids
AtherosclerosisU-shape relationship between change in dietary cholesterol absorption and plasma lipoprotein responsiveness and evidence for extreme interindividual variation in dietary cholesterol absorption in humans.
AlcoholUsing Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures
Diet BrainVagotomy and subsequent risk of Parkinson's disease.
DietVan Damme, Handbook of Plant Lectins
AtherosclerosisVascular effects of diet supplementation with plant sterols.
DietVery-low-carbohydrate diets and preservation of muscle mass
DietVitamin C loss in vegetables during storage, preparation and distribution in restaurants
Vitamin DVitamin D and Sunlight: Strategies for Cancer Prevention and Other Health Benefits
Vitamin DVitamin D as a promising anticancer agent
Vitamin DVitamin D deficiency is associated with anxiety and depression in fibromyalgia
DietVitamin retention in eight fruits and vegetables: a comparison of refrigerated and frozen storage.
AtherosclerosisVLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial.
Diet BrainVoluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice.
ObesityWhat is metabolic syndrome, and why are children getting it?
BrainWhich comes first? The obesity or the insulin? The behavior or the biochemistry?
AtherosclerosisWill the Real Cholesterol Transporter Please Stand Up
Diet Caloric Intake and Aging
Diet Circadian physiology of metabolism.
Diet A time to fast.
Diet Fasting: molecular mechanisms and clinical applications.
Diet Intermittent metabolic switching, neuroplasticity and brain health.
Diet An Evolutionary Perspective on Why Food Overconsumption Impairs Cognition.https://doi.org/10.1016/j.tics.2019.01.003
Diet Calorie restriction improves health, survival in rhesus monkeys
Diet Caloric restriction and cancer: molecular mechanisms and clinical implications.
Diet Fasting and cancer: molecular mechanisms and clinical application
Diet Caloric restriction.
Diet Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting.
Diet Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.
Diet Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects.
Diet Starvation in man.
Diet GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans.
Diet The effect of short-term fasting on liver and skeletal muscle lipid, glucose, and energy metabolism in healthy women and men.
Diet Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma
Diet Hypocaloric diets and ketogenesis in the management of obese gestational diabetic women.
Diet Short-term very low calorie diet reduces oxidative stress in obese type 2 diabetic patients.
Diet The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women.
Diet β-Hydroxybutyrate: A Signaling Metabolite.
Diet Understanding the Physiology of FGF21.
Diet The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man
Diet It takes two to tango: NAD+ and sirtuins in aging/longevity control
Diet Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers.
Diet Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake.
Diet The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women.
Diet Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan.
Diet Fat Maintenance Is a Predictor of the Murine Lifespan Response to Dietary Restriction
Diet Genetic Variation in the Murine Lifespan Response to Dietary Restriction: from Life Extension to Life Shortening
Diet Caloric restriction delays disease onset and mortality in rhesus monkeys.
Diet Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.
Diet Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Supports the Rate of Living and Oxidative Damage Theories of Aging
Diet Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism.
Diet Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges.
Diet Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males
Diet Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia
Diet From the Cover: Caloric restriction improves memory in elderly humans
Diet Cognitive Effects of Intentional Weight Loss in Elderly Obese Individuals With Mild Cognitive Impairment
Diet The effect of caloric restriction on working memory in healthy non-obese adults.
Diet Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats.
Diet Caloric restriction and human longevity: what can we learn from the Okinawans?
Diet Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC404101/
Diet Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial.
Diet Calorie restriction in humans: An update.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315691/
Diet Design and Conduct of the CALERIE Study: Comprehensive Assessment of the Long-term Effects of Reducing Intake of Energy
Diet Significant improvement in cardiometabolic health in healthy nonobese individuals during caloric restriction-induced weight loss and weight loss maintenance.
Diet Effect of Calorie Restriction on Mood, Quality of Life, Sleep, and Sexual Function in Healthy Nonobese Adults: The CALERIE 2 Randomized Clinical Trial.
Diet Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial.
Diet A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity
Diet Potential Benefits and Harms of Intermittent Energy Restriction and Intermittent Fasting Amongst Obese, Overweight and Normal Weight Subjects—A Narrative Review of Human and Animal Evidence
Diet Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin
Diet Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even Without Weight Loss in Men with Prediabetes
Diet Effect of Alternate-Day Fasting onWeight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adult
Diet Caloric Restriction Alone and with Exercise Improves CVD Risk in Healthy Non-Obese Individuals
Diet Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulations
Diet Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats
Diet Caloric restriction may reverse age-related autonomic decline in humans.
Diet Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial
Diet When less may be more: calorie restriction and response to cancer therapy.
Diet Energy restriction and the prevention of breast cancer.
Diet Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R's through dietary manipulation.
Diet Cancer metabolism: a therapeutic perspective.
Diet Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction.
Diet FoxO1 is involved in the antineoplastic effect of calorie restriction.
Diet The life-extending effect of dietary restriction requires Foxo3 in mice.
Diet Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer
Diet Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up
Diet Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
Diet Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Diet SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice.
Diet Diet-induced weight loss in obese children with asthma: a randomized controlled trial.
Diet A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.
Diet Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota.
Diet Effect of intermittent vs. daily calorie restriction on changes in weight and patient-reported outcomes in people with multiple sclerosis
Diet Fasting followed by vegetarian diet in patients with rheumatoid arthritis: a systematic review.
Diet Reducing elective vascular surgery perioperative risk with brief preoperative dietary restriction.
Diet Preoperative dietary restriction reduces intimal hyperplasia and protects from ischemia-reperfusion injury.
Diet Preoperative very low-calorie diet and operative outcome after laparoscopic gastric bypass: a randomized multicenter study
Diet Short-term caloric restriction exerts neuroprotective effects following mild traumatic brain injury by promoting autophagy and inhibiting astrocyte activation.
Diet Effects of Intermittent Fasting on Health, Aging, and Disease
DietLiver-derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis.
Diet DietCalorie restriction and cancer prevention: metabolic and molecular mechanisms
Atherosclerosis Clinical implications of discordance between low-density lipoprotein cholesterol and particle number.
Atherosclerosis Mortality among patients with familial hypercholesterolemia: a registry-based study in Norway, 1992-2010.
Atherosclerosis The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease.
Atherosclerosis MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.
Atherosclerosis Increased coagulation factor VIII activity in patients with familial hypercholesterolemia.
Atherosclerosis Increased plasma fibrinogen and platelet-aggregates in type II hyperlipoproteinaemia.
Atherosclerosis LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature.
Atherosclerosis Increased coagulation factor VIII activity in patients with familial hypercholesterolemia.
Atherosclerosis Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction.
Atherosclerosis Carbohydrate-induced and fat-induced lipemia.
Atherosclerosis Evidence from randomised controlled trials did not support the introduction of dietary fat guidelines in 1977 and 1983: a systematic review and meta-analysis
Atherosclerosis Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT).
Atherosclerosis Hypercholesteremia with predisposition to atherosclerosis, an inborn error of lipid metabolism.
Atherosclerosis Familial Hypercholesterolemia: Genetic Metabolic Study
Atherosclerosis Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study.
Atherosclerosis Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review
Atherosclerosis Essential fatty acids, degree of unsaturation, and effect of corn (maize) oil on the serum-cholesterol level in man.
Atherosclerosis Corn Oil in Treatment of Ischaemic Heart Disease
Atherosclerosis Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial
Atherosclerosis Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
Atherosclerosis How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease.
Atherosclerosis Statin therapy and risk of developing type 2 diabetes: a meta-analysis
Atherosclerosis Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database
Atherosclerosis Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.
Atherosclerosis Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort
Atherosclerosis Long-term statin use and risk of ductal and lobular breast cancer among women 55 to 74 years of age.
Atherosclerosis The effect of HMG-CoA reductase inhibitors on cognition in patients with Alzheimer's dementia: a prospective withdrawal and rechallenge pilot study.
Atherosclerosis Formal comment on “Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease
Atherosclerosis Inborn coagulation factors are more important cardiovascular risk factors than high LDL-cholesterol in familial hypercholesterolemia.
Atherosclerosis Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
Atherosclerosis Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S.
Cancer Hormonal events during female puberty in relation to breast cancer risk.
Obesity Metabolic complications of obesity in childhood and adolescence: more than just diabetes.
Obesity [Obesity--significance in adolescence and for reproduction].
Obesity Effects of obesity on growth and puberty.
Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives
Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature
Nutritional ketosis delays the onset of isoflurane induced anesthesia
Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models
Concentration-Dependent Effects of a Dietary Ketone Ester on Components of Energy Balance in Mice.
Anticatabolic Effects of Ketone Bodies in Skeletal Muscle.
Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements.
Commentary: Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists.
Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats.
The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats.
Adenosine A1 Receptor Antagonism Abolished the Anti-seizure Effects of Exogenous Ketone Supplementation in Wistar Albino Glaxo Rijswijk Rats.
Need for new review of article on ketogenic dietary regimes for cancer patients.
Press-pulse: a novel therapeutic strategy for the metabolic management of cancer.
Corrigendum: Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats.
Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention.
Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.
The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.
Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology.
Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer.
Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure.
Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.
Different calorie restriction treatments have similar anti-seizure efficacy.
Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats.
Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model.
Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats.
Delaying latency to hyperbaric oxygen-induced CNS oxygen toxicity seizures by combinations of exogenous ketone supplements.
Exogenous Ketone Supplementation Decreased the Lipopolysaccharide-Induced Increase in Absence Epileptic Activity in Wistar Albino Glaxo Rijswijk Rats
Metabolic therapy with Deanna Protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model.
Metabolic therapy: a new paradigm for managing malignant brain cancer.
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Fueling Performance: Ketones Enter the Mix.
Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle.
The Effects of Ketogenic Dieting on Body Composition, Strength, Power, and Hormonal Profiles in Resistance Training Males.
Targeting the Warburg effect for cancer treatment: Ketogenic diets for management of glioma
Cancer as a metabolic disease: implications for novel therapeutics.
A Ketogenic Pill for Glioblastoma
Exploring the Viability of Exogenous Ketones as Weight Loss Supplements
β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle.
A role for sphingolipids in the pathophysiology of obesity-induced inflammation.
Insulin increases ceramide synthesis in skeletal muscle
Improvement in Glycemic and Lipid Profiles in Type 2 Diabetics with a 90-Day Ketogenic Diet.
Per-Arnt-Sim Kinase (PASK) Deficiency Increases Cellular Respiration on a Standard Diet and Decreases Liver Triglyceride Accumulation on a Western High-Fat High-Sugar Diet.
Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice.
Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration.
Volumetric analysis of central body fat accurately predicts incidence of diabetes and hypertension in adults.
MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.
Ceramides as modulators of cellular and whole-body metabolism.
Sphingolipids and hepatic steatosis.
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.
Cancer Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet.
Cancer The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Cancer The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model.
Cancer Metabolism and glioma therapy.
Cancer The ketogenic diet for the treatment of malignant glioma.
Cancer The ketogenic diet for the treatment of glioma: insights from genetic profiling.
Cancer The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma
Social How white and African Americans view their health and social problems. Different experiences, different expectations
Cancer Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy
Dietary restriction selectively decreases glucocorticoid receptor expression in the hippocampus and cerebral cortex of rats.
Existing data suggest that Alzheimer's disease is preventable
Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice.
Contributions of mitochondrial alterations, resulting from bad genes and a hostile environment, to the pathogenesis of Alzheimer's disease.
Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems.
The need for controlled studies of the effects of meal frequency on health.
Energy intake, meal frequency, and health: a neurobiological perspective.
Cardioprotection by intermittent fasting in rats.
Caloric restriction and intermittent fasting: two potential diets for successful brain aging.
Energy intake and amyotrophic lateral sclerosis.
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.
Dietary factors, hormesis and health.
Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender.
Neurotrophic factors in autonomic nervous system plasticity and dysfunction.
Impact of energy intake and expenditure on neuronal plasticity.
Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males.
Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment.
Cardioprotective effect of intermittent fasting is associated with an elevation of adiponectin levels in rats.
Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders.
Perspective: Does brown fat protect against diseases of aging?
Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression.
Age and energy intake interact to modify cell stress pathways and stroke outcome
Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging.
Tweaking energy metabolism to prevent and treat neurological disorders.
Chronic alternate-day fasting results in reduced diastolic compliance and diminished systolic reserve in rats.
Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease.
Perturbed Energy Metabolism and Neuronal Circuit Dysfunction in Cognitive Impairment
Energy restriction negates NMDA receptor antagonist efficacy in ischemic stroke.
Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health.
Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein.
Activity-dependent, stress-responsive BDNF signaling and the quest for optimal brain health and resilience throughout the lifespan
Energy intake and exercise as determinants of brain health and vulnerability to injury and disease.
BDNF mediates adaptive brain and body responses to energetic challenges.
Exercise, energy intake, glucose homeostasis, and the brain.
Challenging Oneself Intermittently to Improve Health
Lifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence.
Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits.
Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges.
Nutritional strategies to optimise cognitive function in the aging brain.
3-Hydroxybutyrate Regulates Energy Metabolism and Induces BDNF Expression in Cerebral Cortical Neurons
Impact of intermittent fasting on health and disease processes
Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance.
Whole-Body Vibration Mimics the Metabolic Effects of Exercise in Male Leptin Receptor–Deficient Mice
Brain metabolism in health, aging, and neurodegeneration
Toll-like Receptor 4 Mediates Fat, Sugar and Umami Taste Preference, and Food Intake and Body Weight Regulation
Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle
In a randomized trial in prostate cancer patients, dietary protein restriction modifies markers of leptin and insulin signaling in plasma extracellular vesicles.
Intermittent metabolic switching, neuroplasticity and brain health.
Metabolic and molecular framework for the enhancement of endurance by intermittent food deprivation
Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States
A mitochondrial uncoupler prodrug protects dopaminergic neurons and improves functional outcome in a mouse model of Parkinson's disease.
A randomized pilot study comparing zero-calorie alternate-day fasting to daily caloric restriction in adults with obesity.
Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis.
An Evolutionary Perspective on Why Food Overconsumption Impairs Cognition.
Chronic Mild Gut Inflammation Accelerates Brain Neuropathology and Motor Dysfunction in α-Synuclein Mutant Mice.
Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia.
Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.
DNP, mitochondrial uncoupling, and neuroprotection: A little dab'll do ya.
Effect of intermittent vs. daily calorie restriction on changes in weight and patient-reported outcomes in people with multiple sclerosis
Effects of a dietary ketone ester on hippocampal glycolytic and TCA cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer’s disease
Effects of Intermittent Fasting on Health, Aging, and Disease.
Enhancing and Extending Biological Performance and Resilience
Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
Impact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease
Intergenerational Metabolic Syndrome and Neuronal Network Hyperexcitability in Autism.
Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes.
Meal frequency and timing in health and disease.
Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies
Mitophagy and Alzheimer’s disease: cellular and molecular mechanisms
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
NAD+ in Brain Aging and Neurodegenerative Disorders.
Nuclear DNA damage signalling to mitochondria in ageing.
Phytochemicals in Ischemic Stroke.
SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice
Transcriptome analysis reveals intermittent fasting-induced genetic changes in ischemic stroke.
Uric acid enhances longevity and endurance and protects the brain against ischemia.
Walking Speed Decline in Older Adults is Associated with Elevated Pro-BDNF in Plasma Extracellular Vesicles
What Doesn't Kill You...
Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment.
Intermittent fasting attenuates inflammasome activity in ischemic stroke.
Telomere Shortening in Neurological Disorders: An Abundance of Unanswered Questions
Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability
BDNF and Exercise Enhance Neuronal DNA Repair by Stimulating CREB-Mediated Production of Apurinic/Apyrimidinic Endonuclease 1
Nutrition and the biology of human ageing: cognitive decline/food intake and caloric restriction.
The neuropathology of obesity: insights from human disease.
Exercise and the brain: a slap on the HAND.
The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.
An Overview of APP Processing Enzymes and Products
Dietary restriction mitigates cocaine-induced alterations of olfactory bulb cellular plasticity and gene expression, and behavior.
The impact of dietary energy intake on cognitive aging.
Adiponectin protects rat hippocampal neurons against excitotoxicity
Acetylation unleashes protein demons of dementia.
Mitochondria and neuroplasticity
Resveratrol commonly displays hormesis: occurrence and biomedical significance.
Metabolic reserve as a determinant of cognitive aging
Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production.
Playtime prevents obesity by brain-mediated fat browning.
Metabolic reserve as a determinant of cognitive aging
Evolutionary Aspects of Human Exercise – Born to Run Purposefully
Irisin Irisin
Irisin Exercise-Induced Irisin, the Fat Browning Myokine, as a Potential Anticancer Agent
Nutrient intake, nutritional status, and cognitive function with aging.
Clinical implications of discordance between low-density lipoprotein cholesterol and particle number.
Mortality among patients with familial hypercholesterolemia: a registry-based study in Norway, 1992-2010.
The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease.
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.
Increased coagulation factor VIII activity in patients with familial hypercholesterolemia.
Increased plasma fibrinogen and platelet-aggregates in type II hyperlipoproteinaemia.
LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature.
Increased coagulation factor VIII activity in patients with familial hypercholesterolemia.
Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction.
Carbohydrate-induced and fat-induced lipemia.
Evidence from randomised controlled trials did not support the introduction of dietary fat guidelines in 1977 and 1983: a systematic review and meta-analysis
Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT).
Hypercholesteremia with predisposition to atherosclerosis, an inborn error of lipid metabolism.
Familial Hypercholesterolemia: Genetic Metabolic Study
Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study.
Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review
Essential fatty acids, degree of unsaturation, and effect of corn (maize) oil on the serum-cholesterol level in man.
Corn Oil in Treatment of Ischaemic Heart Disease
Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease.
Statin therapy and risk of developing type 2 diabetes: a meta-analysis
Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database
Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.
Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort
Long-term statin use and risk of ductal and lobular breast cancer among women 55 to 74 years of age.
The effect of HMG-CoA reductase inhibitors on cognition in patients with Alzheimer's dementia: a prospective withdrawal and rechallenge pilot study.
Formal comment on “Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease
Inborn coagulation factors are more important cardiovascular risk factors than high LDL-cholesterol in familial hypercholesterolemia.
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S.
Treatment of obesity: Developments of the past 150 years
Letter on corpulence : addressed to the public
Long term effects of ketogenic diet in obese subjects with high cholesterol level.
Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base.
Fat in the Diet and Mortality from Heart Disease
β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle.
A role for sphingolipids in the pathophysiology of obesity-induced inflammation.
Insulin increases ceramide synthesis in skeletal muscle
Improvement in Glycemic and Lipid Profiles in Type 2 Diabetics with a 90-Day Ketogenic Diet.
Per-Arnt-Sim Kinase (PASK) Deficiency Increases Cellular Respiration on a Standard Diet and Decreases Liver Triglyceride Accumulation on a Western High-Fat High-Sugar Diet.
Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice.
Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration.
Volumetric analysis of central body fat accurately predicts incidence of diabetes and hypertension in adults.
MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.
Ceramides as modulators of cellular and whole-body metabolism.
Sphingolipids and hepatic steatosis.
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.
Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives
Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature
Nutritional ketosis delays the onset of isoflurane induced anesthesia
Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models
Concentration-Dependent Effects of a Dietary Ketone Ester on Components of Energy Balance in Mice.
Anticatabolic Effects of Ketone Bodies in Skeletal Muscle.
Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements.
Commentary: Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists.
Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats.
The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats.
Adenosine A1 Receptor Antagonism Abolished the Anti-seizure Effects of Exogenous Ketone Supplementation in Wistar Albino Glaxo Rijswijk Rats.
Need for new review of article on ketogenic dietary regimes for cancer patients.
Press-pulse: a novel therapeutic strategy for the metabolic management of cancer.
Corrigendum: Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats.
Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention.
Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.
The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.
Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology.
Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer.
Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure.
Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.
Different calorie restriction treatments have similar anti-seizure efficacy.
Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats.
Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model.
Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats.
Delaying latency to hyperbaric oxygen-induced CNS oxygen toxicity seizures by combinations of exogenous ketone supplements.
Exogenous Ketone Supplementation Decreased the Lipopolysaccharide-Induced Increase in Absence Epileptic Activity in Wistar Albino Glaxo Rijswijk Rats
Metabolic therapy with Deanna Protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model.
Metabolic therapy: a new paradigm for managing malignant brain cancer.
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Fueling Performance: Ketones Enter the Mix.
Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle.
The Effects of Ketogenic Dieting on Body Composition, Strength, Power, and Hormonal Profiles in Resistance Training Males.
Targeting the Warburg effect for cancer treatment: Ketogenic diets for management of glioma
Cancer as a metabolic disease: implications for novel therapeutics.
A Ketogenic Pill for Glioblastoma
Exploring the Viability of Exogenous Ketones as Weight Loss Supplements
Statin wars: have we been misled about the evidence? A narrative review
The Anglo-Scandinavian Cardiac Outcomes Trial lipid lowering arm: extended observations 2 years after trial closure.
Measles: low uptake blamed on “incredulity and hostility” towards doctors
Statins for primary prevention of cardiovascular disease
Statin adherence and risk of accidents: a cautionary tale.
Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
A Reappraisal of the Lipid Hypothesis
Opening up data at the European Medicines Agency
Statins: we need an independent review
Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet.
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model.
Metabolism and glioma therapy.
The ketogenic diet for the treatment of malignant glioma.
The ketogenic diet for the treatment of glioma: insights from genetic profiling.
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma
How white and African Americans view their health and social problems. Different experiences, different expectations
Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy
Insulin Exacerbates Inflammation in Fibroblast-Like Synoviocytes.
Feasibility and efficacy data from a ketogenic diet intervention in Alzheimer's disease
Defining “FGF21 Resistance” during obesity: Controversy, criteria and unresolved questions
High-dose ω-3 Fatty Acid Plus Vitamin D3 Supplementation Affects Clinical Symptoms and Metabolic Status of Patients with Multiple Sclerosis: A Randomized Controlled Clinical Trial.
Bioavailability of alpha-linolenic acid in subjects after ingestion of three different forms of flaxseed.
Insulin resistance disrupts cell integrity, mitochondrial function and inflammatory signaling in lymphatic endothelium
Substitution of linoleic acid with α-linolenic acid or long chain n-3 polyunsaturated fatty acid prevents Western diet induced nonalcoholic steatohepatitis
Ketogenic diet for schizophrenia: Nutritional approach to antipsychotic treatment.
Long-term high-protein diet intake reverts weight gain and attenuates metabolic dysfunction on high-sucrose-fed adult rats
Egg consumption may improve factors associated with glycemic control and insulin sensitivity in adults with pre- and type II diabetes.
Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits
Successful treatment of obesity and insulin resistance via ketogenic diet status post Roux-en-Y
Ketogenic diet regulates the antioxidant catalase via the transcription factor PPARγ2.
Insulin Exacerbates Inflammation in Fibroblast-Like Synoviocytes.
Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function
Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome.
Brain Insulin Resistance Triggers Early Onset Alzheimer Disease in Down Syndrome
Characterising Hyperinsulinaemia Induced Insulin Resistance in Human Skeletal Muscle Cells
Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes.
Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research
Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature | Psychiatry
Stigma in attention deficit hyperactivity disorder
Ketones Suppress Brain Glucose Consumption
Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance
The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling. - PubMed - NCBI
Lysosomal Regulation of mTORC1 by Amino Acids in Mammalian Cells
Board-certified Health Coaches?What Integrative Physicians Need to Know
Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metab…
Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study - ScienceDirect
Grip Strength as an Indicator of Health-Related Quality of Life in Old Age—A Pilot Study
Significance of diet in treated and untreated acne vulgaris
Geographical variation in the prevalence of obesity, metabolic syndrome, and diabetes among US adults
JAMA Network Treating Overweight Patients
The Surprising History of the “HRmax=220-age” Equation
Age-predicted maximal heart rate revisited. - PubMed - NCBI
Fructose, insulin resistance, and metabolic dyslipidemia
The proteasome: Overview of structure and functions
Author: Puchowicz, Michelle
Shielding methods and products against man-made Electromagnetic Fields: Protection versus risk - ScienceDirect
Mechanism of action of electromagnetic fields on cells
A Mechanism for Action of Oscillating Electric Fields on Cells - ScienceDirect
‎Symptoms Attributed to Radiofrequency Electromagnetic Fields
Electromagnetic fields instantaneously modulate nitric oxide signaling in challenged biological systems.
Voltage-gated calcium channels.
Neuronal Voltage-Gated Calcium Channels: Structure, Function, and Dysfunction - ScienceDirect
EMR and plants: published papers in peer-reviewed scientific journals that show (possible) EMR effects
High frequency (900 MHz) low amplitude (5 V m-1) electromagnetic field: A genuine environmental stimulus that affects transcription, translation, calcium and energy charge in tomato
EMF & Cancer: Epidemiologic Evidence To Date
Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects
Scientific evidence contradicts findings and assumptions of Canadian Safety Panel 6: microwaves act through voltage-gated calcium channel activation to induce biological impacts at non-thermal levels
A Synonymous Single Nucleotide Polymorphism in ∆F508 CFTR Alters the Secondary Structure of the mRNA the Expression of the Mutant Protein
Toxocariasis and Ingestion of Raw Cow Liver in Patients with Eosinophilia
A high-sugar diet rapidly enhances susceptibility to colitis via depletion of luminal short-chain fatty acids in mice
SNPs of myostatin (MSTN) gene and their association with growth traits in three bay scallop (Argopecten irradians) populations
A Mutation in the Myostatin Gene Increases Muscle Mass and Enhances Racing Performance in Heterozygote Dogs
The U.S. Insulin Crisis — Rationing a Lifesaving Medication Discovered in the 1920s
Milk Intolerance, Beta-Casein and Lactose
Effects of Statins on Memory, Cognition, and Brain Volume in the Elderly
Aging, Cellular Senescence, and Cancer
Chemotaxis signaling systems in model beneficial plant-bacteria associations.
Evolution of lactase persistence: an example of human niche construction
The human lactase persistence-associated SNP −13910*T enables in vivo functional persistence of lactase promoter-reporter transgene expression
Shedding “UV” Light on Endogenous Opioid Dependence - ScienceDirect
Essentiality of boron for healthy bones and joints.
Sugar Industry and Coronary Heart Disease Research: A Historical Analysis of Internal Industry Documents
The Epigenetic Impact of Cruciferous Vegetables on Cancer Prevention
Advanced glycation end products and diabetic retinopathy
Methionine sulfoxide reductase A: Structure, function and role in ocular pathology
Dissecting the mechanisms and molecules underlying the potential carcinogenicity of red and processed meat in colorectal cancer (CRC): an overview on the current state of knowledge
Fructose-induced inflammation, insulin resistance and oxidative stress: A liver pathological triad effectively disrupted by lipoic acid.
Red Wine Polyphenols Alone or in Association with Ethanol Prevent Hypertension, Cardiac Hypertrophy, and Production of Reactive Oxygen Species in the Insulin-Resistant Fructose-Fed Rat
Role of fructose in glycation and cross-linking of proteins
Molecular basis of arterial stiffening: role of glycation - a mini-review.
Role of the Maillard reaction in diabetes mellitus and diseases of aging.
A genomic predictor of lifespan in vertebrates
Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle
Distinct DNA methylomes of newborns and centenarians
A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue
The thin-fat phenotype and global metabolic disease risk.
Weight Training Plus Aerobics Is Best to Ward Off Obesity
Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation.
Frontiers | Maternal Age at Holocaust Exposure and Maternal PTSD Independently Influence Urinary Cortisol Levels in Adult Offspring
Ketogenic diet and adipose tissue inflammation—a simple story? Fat chance!
Statin wars: have we been misled about the evidence? A narrative review
Is everything we eat associated with cancer? A systematic cookbook review.
Isothiocyanates and Xenobiotic Detoxification
Why Most Published Research Findings Are False
Falsified papers in high-impact journals were slow to retract and indistinguishable from nonfraudulent papers.
Coronary artery calcium scanning: past, present, and future.
Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver.
Dietary linoleic acid is required for development of experimentally induced alcoholic liver injury.
Alcoholic Liver Disease: Update on the Role of Dietary Fat
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity.
Adipose tissue immune response: novel triggers and consequences for chronic inflammatory conditions.
Linoleic acid recommendations--A house of cards.
The importance of the ratio of omega-6/omega-3 essential fatty acids.
Irisin Is irisin a human exercise gene?
Irisin Irisin, Light My Fire
Irisin Lower circulating irisin is associated with type 2 diabetes mellitus
Irisin Irisin, Turning Up the Heat
Irisin Circulating Irisin in Relation to Insulin Resistance and the Metabolic Syndrome
Irisin Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
Irisin Evidence against a Beneficial Effect of Irisin in Humans
Irisin FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine
Irisin Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance
Irisin Irisin Enhances Osteoblast Differentiation In Vitro
Irisin Irisin: A renaissance in metabolism?
Irisin Irisin in patients with nonalcoholic fatty liver disease
Irisin Irisin – a myth rather than an exercise-inducible myokine
Irisin The myokine irisin increases cortical bone mass
Exercise Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation
Exercise Metabolism of ketone bodies during exercise and training:physiological basis for exogenous supplementation
Exercise Fueling Performance: Ketones Enter the Mix
Exercise Does Strength-Promoting Exercise Confer Unique Health Benefits?
Exercise The glucose‐lowering effects of exogenous ketones: is there therapeutic potential?
Exercise Sarcopenia Is Recognized as an Independent Condition by an International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM) Code.
Exercise Of Greek Heroes, Wiggling Worms, Mighty Mice, and Old Body Builders
Exercise Gait Speed and Survival in Older Adults
Exercise Association between muscular strength and mortality in men: prospective cohort study
Exercise Assessment of the Determinants of Healthy Ageing among the Rural Elderly of North-Eastern Nigeria
Exercise Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest.
Exercise Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress.
Exercise Effect of 10 days of bed rest on skeletal muscle in healthy older adults.
Exercise Protecting muscle mass and function in older adults during bed rest.
Exercise Chronic exercise preserves lean muscle mass in masters athletes.
Exercise The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for Non-Insulin Dependent Diabete Mellitus
Exercise Development of Pharmacotherapies for the Treatment of Sarcopenia.
Exercise American College of Sports Medicine position stand. Exercise and physical activity for older adults.
Exercise Comparison of time-matched aerobic, resistance, or concurrent exercise training in older adults
Exercise Uncomplicated resistance training and health-related outcomes: evidence for a public health mandate.
Exercise The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people.
Exercise Repeated sit-to-stand exercise enhances muscle strength and reduces lower body muscular demands in physically frail elders.
Exercise Reversal of age-associated frailty by controlled physical exercise: The pre-clinical and clinical evidences
Effects of dairy products consumption on inflammatory biomarkers among adults: a systematic review and meta-analysis of randomized controlled trials
β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
Vitamin D increases expression of the tyrosine hydroxylase gene in adrenal medullary cells.
Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1.
Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism.
Accuracy of Smartphone-Based Pulse Oximetry Compared with Hospital-Grade Pulse Oximetry in Healthy Children.
Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line
Tissue Plasminogen Activator (tPA) Expression Is Increased by Islet Amyloid Formation In Vitro
Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes.
Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption.
Transcription regulators and hormones involved in the development of brown fat and white fat browning: transcriptional and hormonal control of brown/beige fat development.
Types of Sedentary Behavior and Risk of Cardiovascular Events and Mortality in Blacks: The Jackson Heart Study
Get up, stand up, stand up for your health! Faculty and student perspectives on addressing prolonged sitting in university settings
Patterns of Sedentary Behavior and Mortality in U.S. Middle-Aged and Older Adults: A National Cohort Study
Do Sitting, Standing, or Treadmill Desks Impact Psychobiological Indicators of Work Productivity?
Section 26.4Important Derivatives of Cholesterol Include Bile Salts and Steroid Hormones
The combined effects of L-theanine and caffeine on cognitive performance and mood.
Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial
Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study
A Novel Intervention Including Individualized Nutritional Recommendations Reduces Hemoglobin A1c Level, Medication Use, and Weight in Type 2 Diabetes
Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled stud
Post hoc analyses of surrogate markers of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis in patients with type 2 diabetes in a digitally supported continuous care intervention: an open-label, non-randomised controlled study
Improvement in patient-reported sleep in type 2 diabetes and prediabetes participants receiving a continuous care intervention with nutritional ketosis
Keto-adaptation Enhances Exercise Performance and Body Composition Responses to Training in Endurance Athletes
Testosterone Physiology in Resistance Exercise and Training: The Up-Stream Regulatory Elements
Carbohydrate Restriction Has a More Favorable Impact on the Metabolic Syndrome Than a Low Fat Diet
Extended Ketogenic Diet and Physical Training Intervention in Military Personnel
Low-carbohydrate Nutrition and Metabolism
Cardiovascular Disease Risk Factor Responses to a Type 2 Diabetes Care Model Including Nutritional Ketosis Induced by Sustained Carbohydrate Restriction at 1 Year: An Open Label, Non-Randomized, Controlled Study
The Effects of Ketogenic Dieting on Body Composition, Strength, Power, and Hormonal Profiles in Resistance Training Males
Dietary Carbohydrate Restriction Improves Metabolic Syndrome Independent of Weight Loss
Paradox of Hypercholesterolaemia in Highly Trained, Keto-Adapted Athletes
Low-carbohydrate Diets for Athletes: What Evidence?
Adrenal Stress and Physical Performance During Military Survival Training
Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study
Keto-adaptation Enhances Exercise Performance and Body Composition Responses to Training in Endurance Athletes
Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health
Metabolic Characteristics of Keto-Adapted Ultra-Endurance Runners
Rethinking Fat as a Fuel for Endurance Exercise
Dietary Carbohydrate Restriction as the First Approach in Diabetes Management: Critical Review and Evidence Base
Dietary Fat: From Foe to Friend?
Beyond Weight Loss: A Review of the Therapeutic Uses of Very-Low-Carbohydrate (Ketogenic) Diets
Performance and Muscle Fiber Adaptations to Creatine Supplementation and Heavy Resistance Training
Testosterone and Cortisol in Relationship to Dietary Nutrients and Resistance Exercise
Effects of Creatine Supplementation and Resistance Training on Muscle Strength and Weightlifting Performance
The Effects of a Korean Ginseng, GINST15, on Hypo-Pituitary-Adrenal and Oxidative Activity Induced by Intense Work Stress
Post Hoc Analyses of Surrogate Markers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Liver Fibrosis in Patients With Type 2 Diabetes in a Digitally Supported Continuous Care Intervention: An Open-Label, Non-Randomised Controlled Study
Comparison of Low Fat and Low Carbohydrate Diets on Circulating Fatty Acid Composition and Markers of Inflammation
A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-Weight Men
Author Correction: Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study
Body Composition and Hormonal Responses to a Carbohydrate-Restricted Diet
Improvement in Patient-Reported Sleep in Type 2 Diabetes and Prediabetes Participants Receiving a Continuous Care Intervention With Nutritional Ketosis
Corrigendum to "Dietary Carbohydrate Restriction as the First Approach in Diabetes Management: Critical Review and Evidence Base" [Nutrition 31 (2015) 1-13]
Strength Nutrition
Dietary Carbohydrate Restriction Induces a Unique Metabolic State Positively Affecting Atherogenic Dyslipidemia, Fatty Acid Partitioning, and Metabolic Syndrome
A Novel Intervention Including Individualized Nutritional Recommendations Reduces Hemoglobin A1c Level, Medication Use, and Weight in Type 2 Diabetes
Endocrinological Roles for Testosterone in Resistance Exercise Responses and Adaptations
Targeting Metabolism With a Ketogenic Diet During the Treatment of Glioblastoma Multiform
Extended Ketogenic Diet and Physical Training Intervention in Military Personnel
Obesity, Growth Hormone and Exercise
Dietary Carbohydrate Restriction Improves Insulin Sensitivity, Blood Pressure, Microvascular Function, and Cellular Adhesion Markers in Individuals Taking Statins
Co-ingestion of Whole Eggs or Egg Whites With Glucose Protects Against Postprandial Hyperglycaemia-Induced Oxidative Stress and Dysregulated Arginine Metabolism in Association With Improved Vascular Endothelial Function in Prediabetic Men
Replacing Carbohydrate During a Glucose Challenge With the Egg White Portion or Whole Eggs Protects Against Postprandial Impairments in Vascular Endothelial Function in Prediabetic Men by Limiting Increases in Glycaemia and Lipid Peroxidation
Whey Protein Supplementation During Resistance Training Augments Lean Body Mass
Modification of Lipoproteins by Very Low-Carbohydrate Diets
Nutritional Aspects of Women Strength Athletes
The Food Matrix and Sterol Characteristics Affect the Plasma Cholesterol Lowering of Phytosterol/Phytostanol
Immune Responses to Resistance Exercise
The Effects of Soy and Whey Protein Supplementation on Acute Hormonal Reponses to Resistance Exercise in Men
Creatine Supplementation. Its Role in Human Performance
A Review of Low-Carbohydrate Ketogenic Diets
The Impact of an Ultramarathon on Hormonal and Biochemical Parameters in Men
Whole Egg Consumption Improves Lipoprotein Profiles and Insulin Sensitivity to a Greater Extent Than Yolk-Free Egg Substitute in Individuals With Metabolic Syndrome
The Influences of Dried Chicory Root and White Lupine Added to Food on Jejunal Morphology: Experimental Study
The Effect of Age, Genotype and Sex on Carcass Traits, Meat Quality and Sensory Attributes of Geese
Very-low-carbohydrate Weight-Loss Diets Revisited
The Relationship Between Hepatocytes and Small Bowel After Early and Short Food Restriction: What the Results Show in Morphometry
Influence of Nutrition on Responses to Resistance Training
Effect of Resistance Training on Resting Metabolic Rate and Its Estimation by a Dual-Energy X-ray Absorptiometry Metabolic Map
The Effects of a Roundtrip trans-American Jet Travel on Physiological Stress, Neuromuscular Performance, and Recovery
The Case for Not Restricting Saturated Fat on a Low Carbohydrate Diet
Effects of Ingesting Protein in Combination With Carbohydrate During Exercise on Endurance Performance: A Systematic Review With Meta-Analysis
The Effects of Nitrate-Rich Supplementation on Neuromuscular Efficiency During Heavy Resistance Exercise
Nonfasting Triglycerides and Cardiovascular Risk
Quantification of Human Central Adipose Tissue Depots: An Anatomically Matched Comparison Between DXA and MRI
Habitual Exercise May Maintain Endothelium-Dependent Dilation in Overweight Postmenopausal Women
l-Carnitine L-Tartrate Supplementation Favorably Affects Biochemical Markers of Recovery From Physical Exertion in Middle-Aged Men and Women
Hydration and Muscular Performance: Does Fluid Balance Affect Strength, Power and High-Intensity Endurance?
Resistance Training and Elite Athletes: Adaptations and Program Considerations
Stored Product Mites (Acari: Astigmata) Infesting Food in Various Types of Packaging
The Influence of Food Restriction on the Small Bowel: Does Intensive Short‑term Food Restriction Lead to Weight Loss?
Scientific Basis and Practical Aspects of Creatine Supplementation for Athletes
The Presence of Symptoms of Testosterone Deficiency in the Exercise-Hypogonadal Male Condition and the Role of Nutrition
Diet and Exercise for Weight Loss: A Review of Current Issues
Carbohydrate Restriction as the Default Treatment for Type 2 Diabetes and Metabolic Syndrome
Cardiovascular and Hormonal Aspects of Very-Low-Carbohydrate Ketogenic Diets
Neuroendocrine-immune Interactions and Responses to Exercise
Dairy Milk Proteins Attenuate Hyperglycemia-Induced Impairments in Vascular Endothelial Function in Adults With Prediabetes by Limiting Increases in Glycemia and Oxidative Stress That Reduce Nitric Oxide Bioavailability
Analysis of Dietary Interventions. A Simple Payoff Matrix for Display of Comparative Dietary Trials